Left-back Gaetan Bong is out of Albion's top-of-the-table Championship clash with Reading on Saturday.
The 28-year-old has missed Brighton's past nine matches with a knee injury but is close to returning to action.
Full-back Liam Rosenior, who has been out since the 2-2 draw at Reading in August with an ankle injury, is nearing a return.
Seagulls boss Chris Hughton said: "Anyone coming back from an injury and getting back into training, there's some barriers to get through as each week goes past.
"But Liam's been training now for about three weeks and is very close."
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